Impaired kidney function associated with cognitive impairment
Summary: Of the patients with dementia, 7% had chronic kidney disease, while 9% had albuminuria, a urinary marker for kidney disease. Chronic kidney disease is associated with a 51% increased risk of developing dementia.
Source: American Society of Nephrology
New research has shown a link between kidney disease and the development of cognitive problems.
The findings will be presented at ASN Kidney Week 2022 from November 3 to November 6.
The study relied on data from the population-based Framingham Heart Study. Among the 2,738 participants without dementia, 187 (7%) had chronic kidney disease and 251 (9%) had albuminuria, a urinary marker of kidney disease.
Albuminuria was associated with signs of silent stroke, and patients with albuminuria had a 65% higher risk of developing mild cognitive impairment or dementia.
Chronic kidney disease was not associated with markers of silent cerebrovascular disease, but was associated with a 51% higher risk of developing dementia.
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“Our results highlight the importance of albuminuria as a cerebrovascular and cognitive risk factor and suggest that there may be additional shared mechanisms of disease in the kidney and brain beyond hypertension,” said author Dearbhla Kelly, MBBChBAO, MSc, DPhil, of St. James’s Hospital, Dublin, Ireland.
About this news about dementia research
Author: Christine Feheley
Source: American Society of Nephrology
Contact: Christine Feheley – American Society of Nephrology
picture: Image is in the public domain
Original Research: The findings will be presented at ASN Kidney Week 2022
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